The top journal of the achievement journal, how to accurately regulate blood sugar in patients with type 2 diabetes? Zhongshan Hospital breaks through through the use of AI systems

Release time:Apr 16, 2024 21:33 PM

Recently, a team led by Li Xiaoying and Chen Ying from the Endocrinology Department of Zhongshan Hospital affiliated with Fudan University, together with a team led by Professor Wang Guangyu from Beijing University of Posts and Telecommunications, published their research results online in the top international medical journal Nature Medicine. For the first time in the world, the joint team proposed to adopt AI system "RL-DITR" based on reinforcement learning algorithm to formulate insulin decision-making strategies, effectively improving the accuracy of insulin treatment programs for patients with type 2 diabetes. The research results can provide personalized and dynamic diagnosis and treatment programs for patients with type 2 diabetes, assist in establishing a hierarchical diagnosis and treatment system, and improve the efficiency of chronic disease management.

China is the largest country of diabetes. According to the latest data, one in every nine adults has diabetes, of which type 2 diabetes accounts for more than 90% of the total number of diabetes, and nearly 50% of patients need insulin injection treatment.

 

How to accurately and efficiently adjust insulin dosage for a large group of diabetes patients? This has always been a difficult problem that has plagued the medical community.

 

How to accurately and efficiently adjust insulin dosage for a large group of diabetes patients? This has always been a difficult problem that has plagued the medical community.


The top journal of the achievement journal, how to accurately regulate blood sugar in patients with type 2 diabetes? Zhongshan Hospital breaks through through the use of AI systems

This system can predict the optimal drug dosage in real-time based on the patient's historical data and current physiological conditions, as well as the differences in insulin response among different patients and changes in insulin demand during disease progression. It can develop personalized, accurate, and dynamic treatment strategies to achieve blood glucose control goals.

 

Traditional insulin dose adjustment mainly relies on the experience of doctors and cannot meet the dynamic changes between individuals. Since 2020, Li Xiaoying, Chen Ying and Professor Wang Guangyu have jointly carried out the research on AI system "RL-DITR" based on innovative algorithms such as reinforcement learning to optimize insulin treatment for patients with type 2 diabetes.

 

This system can predict the optimal drug dosage in real-time based on the patient's historical data and current physiological conditions, as well as the differences in insulin response among different patients and changes in insulin demand during disease progression. It can develop personalized, accurate, and dynamic treatment strategies to achieve blood glucose control goals.

 


The top journal of the achievement journal, how to accurately regulate blood sugar in patients with type 2 diabetes? Zhongshan Hospital breaks through through the use of AI systems

Gu Jianying, Secretary of the Party Committee of Zhongshan Hospital Affiliated to Fudan University, stated that building a digital healthcare world and a new ecosystem of medical services is the hospital's pursuit. The hospital deeply integrates new technologies such as 5G, artificial intelligence, big data, and digital twins with high-quality medical resources to create the first "5G+digital twin smart medical ecosystem" in the country.

 

Research has found that compared to other artificial intelligence models and current clinical standard protocols, RL-DITR is closer to the judgment of doctors with rich clinical experience. Compared with their recommended insulin dosage, the difference is only 1.2 units. At the same time, it increases the percentage of time for patients to meet glucose standards by 24.1% and does not cause serious consequences such as hypoglycemia or ketoacidosis.

Nine medical experts from Shanghai who helped the residents of Karamay in Xinjiang free clinic, spanning more than 4000 kilometers Father | Expert | Shanghai
Nine medical experts from Shanghai who helped the residents of Karamay in Xinjiang free clinic, spanning more than 4000 kilometers Father | Expert | Shanghai

At the arrival of the sixth "Chinese Doctor's Day", nine medical experts from Shanghai, including Renji Hospital affiliated to Shanghai Jiaotong University School of Medicine, Tongji Hospital affiliated to Tongji University, Eye, Ear, Nose and Throat Hospital affiliated to Fudan University, Shanghai Dermatology Hospital, and China Welfare Society International Peace Maternal and Child Health Care Center, including neurology, urology, otorhinolaryngology, ophthalmology, thyroid surgery, breast surgery, hematology, geriatrics, and dermatology, went to Karamay Central Hospital and Karamay Third People's Hospital to carry out free clinic activities. Among them, 6 experts are doctors dispatched by Tongji Hospital to aid Xinjiang, and 3 experts have traveled over 4000 kilometers to Ke to help local patients clarify their doubts. Urumqi residents drove over 400 kilometers with their father to a free clinic, where Patiguli underwent a small physical examination

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Experts remind us to pay attention to these details. Nail beautification is too frequent and toenails are cut too much. Ten nail clinics open full moon surgery | nail bed | clinic

"Thank you Director Liu for helping me solve a big problem! I've been struggling with paronychia for two years. I had to pull out my toenails twice before, but they didn't grow well. I kept getting inflamed and my mentality was about to collapse. This time, the problem has finally been completely solved." In the outpatient consultation room of the Tenth People's Hospital of Shanghai, Miss Zhang expressed her sincere gratitude to Liu Guangpeng, the director of plastic surgery. At the beginning of 2021, Xiaozhang accidentally cut his toenails too deep, injuring the nail bed. Although he disinfected it with iodine at the first time, he didn't expect to become inflamed a few days later. His entire first toe was red, swollen, and painful, and he even limped while walking. External use of iodine is ineffective, oral antibiotics are ineffective, and the only option is to choose toenail removal that sounds very painful. I originally thought that pulling out my toenails would remove the old and replace the new, but I never expected that the newly grown toenails would always "burrow into the flesh", causing inflammation to recur,

Some family doctors have also opened a special clinic for diabetes... 60% of residents in this district of Shanghai are diagnosed and treated in Fengxian | residents | community
Some family doctors have also opened a special clinic for diabetes... 60% of residents in this district of Shanghai are diagnosed and treated in Fengxian | residents | community

Fengxian is located in the remote suburbs, with limited medical resources. Community diagnosis and treatment have become the top priority for residents' health. How to build a good network base to serve the people? The reporter recently learned from the district health commission that based on the actual situation of the region, taking into account the size of the service population and the trend of population introduction, the district health commission is promoting the horizontal integration of community health resources. Residents are willing to "vote with their feet" to choose the community, and the solid foundation and warm service of community family doctors are indispensable. Data shows that there are currently 549 general practitioners in Fengxian District. Last year, the proportion of community diagnosis and treatment accounted for 49% of the total diagnosis and treatment in the district. In the first half of this year, the proportion of community diagnosis and treatment has increased to 60%. Wang Tao is a family doctor at the Xidu Community Health Service Center in Fengxian District who has been committed to the community for ten years and has signed contracts with more than 1900 community residents

In this regional medical center, patients make sachet masks to feel the warmth of home. The Dragon Boat Festival medical center | patients | sachets
In this regional medical center, patients make sachet masks to feel the warmth of home. The Dragon Boat Festival medical center | patients | sachets

Today is the traditional Dragon Boat Festival. As a regional medical center, Shibei Hospital of Jing'an District organized a special "love on the left and accompany on the right" activity to welcome the Dragon Boat Festival. The patients and their families wrapped Zongzi together to make sachets and feel the warmth of home. It is reported that the Elderly Rehabilitation Department of Shibei Hospital is a key discipline in Jing'an District, with 80% of hospitalized patients being over 70 years old, including those aged 90 or 100. During the meticulous treatment of the elderly, the Rehabilitation Department integrates family oriented services throughout, creating a humane "warm service" and building a harmonious doctor-patient relationship. Shu Jin, director of the Elderly Rehabilitation Department, said that with the arrival of the Dragon Boat Festival, medical staff have found that a small number of patients lack family companionship and their psychological and emotional needs cannot be met. The hospital's social work department and department medical staff work together to build a "heart to heart bridge" for doctor-patient interaction and two-way communication,

The annual throat preservation rate is nearly 80%, and Shanghai research was included in the International Annual Conference: Immunotherapy for locally advanced head and neck tumors | Patients | Local
The annual throat preservation rate is nearly 80%, and Shanghai research was included in the International Annual Conference: Immunotherapy for locally advanced head and neck tumors | Patients | Local

At the recent 2023 Annual Meeting of the American Society of Clinical Oncology, research from Fudan University Affiliated Cancer Hospital was quite impressive: in the field of head and neck tumors, "induction chemotherapy combined with treprizumab can be used for laryngeal preservation treatment in patients with locally advanced laryngeal/hypopharyngeal cancer. The results of the Phase II clinical trial showed a one-year laryngeal preservation rate of 79.4%." The first author of this study, abbreviated as INSIGHT, is Professor Xiaomin Qu from Fudan University Affiliated Cancer Hospital, and the corresponding authors are Professor Yu Wang and Professor Xiayun He. It is reported that laryngeal cancer and hypopharyngeal cancer are one of the most common head and neck squamous cell carcinoma in China, with the incidence rate accounting for about 20% of head and neck squamous cell carcinoma. Due to the insidious symptoms of the disease, the patient was diagnosed later and had a poor prognosis. Previously, surgical resection was used to prolong survival. With the development of multidisciplinary comprehensive treatment, diagnosis and treatment

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