Experts remind us to pay attention to these details. Nail beautification is too frequent and toenails are cut too much. Ten nail clinics open full moon surgery | nail bed | clinic

Release time:Apr 14, 2024 10:26 AM

"Thank you Director Liu for helping me solve a big problem! I've been struggling with paronychia for two years. I had to pull out my toenails twice before, but they didn't grow well. I kept getting inflamed and my mentality was about to collapse. This time, the problem has finally been completely solved." In the outpatient consultation room of the Tenth People's Hospital of Shanghai, Miss Zhang expressed her sincere gratitude to Liu Guangpeng, the director of plastic surgery.

At the beginning of 2021, Xiaozhang accidentally cut his toenails too deep, injuring the nail bed. Although he disinfected it with iodine at the first time, he didn't expect to become inflamed a few days later. His entire first toe was red, swollen, and painful, and he even limped while walking. External use of iodine is ineffective, oral antibiotics are ineffective, and the only option is to choose toenail removal that sounds very painful. I originally thought that pulling out my toenails would remove the old and make a new look, but I never expected that the newly grown toenails would always "burrow into the flesh", causing inflammation to recur and the toes to become very unsightly. However, all of this is just the beginning. Not long after, inflammation made a comeback, and the previous process was repeated. And this time, luck seems to be even worse, as the infection persists and the toenails and toes become increasingly ugly

After this year's Dragon Boat Festival, Xiao Zhang immediately hung up when he learned that the plastic surgery department of Ten Hospitals had opened an outpatient clinic for nail diseases, which could solve treatment and plastic surgery problems in a one-stop manner. In response to the severe damage to the nail bed, Liu Guangpeng gave up the commonly used "overall nail removal surgery" in surgery and instead implemented "partial nail removal surgery+correction of soft tissue flap around the nail" from the perspective of a plastic surgeon. In this way, it not only removes necrotic tissue caused by long-term inflammation, but also maximizes the regular repair of toenails and local skin, avoiding the recurrence of ingrown nails and excessive proliferation of connective tissue during the inflammation repair process.

After nearly a month of recovery, Xiaozhang finally bid farewell to the two year long problem of paronychia. Not only has the inflammation completely subsided, but the originally bumpy nail bed and the hideous skin around the nails have also completely recovered. She can now wear sandals confidently again.

Although the nails are small, there are many troubles. Since its establishment on June 25th this year, the specialized nail disease outpatient department of the Plastic Surgery Department of Ten Hospitals has received dozens of patients. In addition to patients like Xiao Zhang who have experienced prolonged paronychia, beautiful women who have suffered damage to their nails, nail beds, and soft tissues around their nails due to improper nail art are also the main patient group in the nail disease outpatient department.

Xiao Li, a college student who is very obsessed with nail decoration, is a regular customer of a nail salon and visits on average once a week. Frequent use of organic solvents such as acetone to clean the ornaments attached to her nails caused significant damage - deformation, brittleness, cracking, roughness... At first, she thought that as long as she stopped doing manicures and waited for the old nails to gradually grow before cutting them off, the new nails would be able to return to their original state. However, due to damage to the nail bed and surrounding soft tissues, the newly formed nails still look repulsive.

Being too shy to reach out has troubled Xiao Li's daily learning and life. After several inquiries, she came to the nail clinic for help. Liu Guangpeng formulated a comprehensive treatment plan for her - to remove the damaged nails under nerve block anesthesia, and then perform a soft tissue flap repair surgery around the nails, providing a flat, beautiful, and healthy growth "soil" for the new nails. Unlike a simple "one pull" procedure, skin flap repair not only allows the nails to grow and grow healthy, but also looks beautiful.

Of course, the nail clinic is not only focused on nail art and plastic surgery needs. A week ago, Liu Guangpeng received a patient named Ms. Wang who had vertical black brown stripes under her nails. Her initial request was just to "whiten" the ribbon, but Liu Guangpeng immediately noticed the huge hidden risk - malignant melanoma! Sure enough, the postoperative pathology confirmed the doctor's diagnosis, but fortunately, the treatment was timely and the patient is still in the stage of in situ cancer.

"Nails are skin accessory tissues that grow on the fingertips and are easily affected by various pathogenic factors in the environment. Their shape, color, texture, and other factors are closely related to the overall health condition. When nails obstruct the view, it is not only necessary to consider from the perspective of cosmetic surgery, but also to pay attention to the hidden health risks behind them." Liu Guangpeng reminds that "in addition to bacterial infections that may cause inflammation, nails are also susceptible to fungal invasion, resulting in decreased transparency, rough texture, and increased thickness of the nail plate. In this case, simply scraping off the diseased nail with physical methods cannot fundamentally solve the problem. Antifungal drugs should be used locally or even throughout the body. In addition, changes in the appearance of nails may also indicate certain systemic diseases, for example." The nail plate is concave in the center and raised around, like a small spoon, which is called "spoon shaped nail" or related to severe anemia, endocrine diseases, etc; If the nails show certain special colors, in addition to melanoma, it may also indicate the presence of lesions in the liver, kidneys, etc. A comprehensive examination should be conducted in a timely manner to detect potential problems.

Why is "Cancer King" immunotherapy ineffective? Fudan Cancer Hospital Reveals New Mechanisms of Immunosuppressive Environment for pancreatic cancer CRIP1 | Tumor | pancreatic cancer
Why is "Cancer King" immunotherapy ineffective? Fudan Cancer Hospital Reveals New Mechanisms of Immunosuppressive Environment for pancreatic cancer CRIP1 | Tumor | pancreatic cancer

Immunotherapy has been proven to achieve significant therapeutic effects in various solid tumors. However, for pancreatic cancer, known as the "king of cancer", immunotherapy has been ineffective. On August 4, Professor Yu Xianjun, Dean of the Cancer Hospital Affiliated to Fudan University, and Shi Si, Associate Professor of Pancreatic Surgery released a research achievement, which first found the key role of cysteine rich protein 1 in shaping the immunosuppressive microenvironment of pancreatic cancer, filled the gap in the research field of immunosuppressive microenvironment of pancreatic cancer, and provided a theoretical basis for precise immunotherapy of pancreatic cancer patients. Ductal adenocarcinoma of the pancreas is the main type of pancreatic cancer, accounting for about 90% of all pancreatic cancer. Due to its high malignancy and poor treatment effectiveness, pancreatic ductal adenocarcinoma has always been one of the most malignant tumors. In recent years, the level of surgical techniques and comprehensive treatment has been achieved

A 14-year-old girl suffers from a rare eye disease and receives support from a public welfare fund. Symptoms of "I haven't looked in the mirror for a long time" | Patient | Public welfare
A 14-year-old girl suffers from a rare eye disease and receives support from a public welfare fund. Symptoms of "I haven't looked in the mirror for a long time" | Patient | Public welfare

A 14-year-old girl has been experiencing symptoms such as protruding pupils, incomplete eye closure, corneal injury, restricted eye movement, and overall fatigue for several years. The physical discomfort and facial abnormalities caused by eye diseases have made her increasingly reticent, and her temperament is vastly different from before. At the Ophthalmology Department of the Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, the pupil has been diagnosed with a rare thyroid ophthalmopathy combined with myasthenia gravis, which requires prompt treatment. However, considering the young age of the pupil, conventional hormone and radiation therapy cannot be used. Therefore, Zhou Huifang, Deputy Director of Ophthalmology and thyroid ophthalmology expert, has developed a targeted drug combined with surgical treatment plan for it, and targeted drug treatment will be performed first. Three months ago, I was hospitalized for one week with mydriasis and received intravenous targeted drug treatment. Afterwards, I went home for observation and followed up on time

The municipal eye disease prevention and treatment center launched the dry eye diagnosis and treatment studio, and the incidence rate of dry eye in China is about 21% to 30% of the meibomian gland | dry eye | eye disease
The municipal eye disease prevention and treatment center launched the dry eye diagnosis and treatment studio, and the incidence rate of dry eye in China is about 21% to 30% of the meibomian gland | dry eye | eye disease

According to the Statistics of Chinese Dry Eye Expert Consensus, the incidence rate of dry eye in China is about 21%~30%, and it is estimated that there are at least 300 million patients nationwide. The Dry Eye Diagnosis and Treatment Studio of Shanghai Eye Disease Prevention and Treatment Center was officially launched today. In the future, the studio will continuously improve the dry eye diagnosis and treatment standards, and form standardized diagnosis and treatment concepts and service models. Suitable technologies will be promoted to the community, allowing residents to enjoy convenient dry eye diagnosis and treatment services at their doorstep. Executive Dean and Party Secretary Gao Wei stated that this is also one of the livelihood service measures recently launched by the hospital around high-quality development and meeting the needs of the people. It is reported that dry eye syndrome is a chronic ocular surface disease caused by multiple factors. The instability of the tear film or imbalance of the ocular surface microenvironment caused by abnormal quality, quantity, and dynamics of tears can be accompanied by ocular surface inflammatory reactions, tissue damage, and nerve abnormalities, resulting in various discomforts in the eyes

The Ninth Hospital has taken the lead in formulating the world's first consensus on core indicators for clinical evaluation of dental implants, which has been officially published in clinical practice
The Ninth Hospital has taken the lead in formulating the world's first consensus on core indicators for clinical evaluation of dental implants, which has been officially published in clinical practice

The International Dental Implant Consensus Report, jointly written by the Ninth People's Hospital affiliated with Shanghai Jiao Tong University School of Medicine and renowned universities in the field of dentistry such as Harvard University, University of Zurich, University of Gothenburg, Columbia University, and University of Frankfurt, has recently been jointly published in top journals in the field of dentistry, including Clinical Periodontology and Clinical Dental Implant Research. This consensus has for the first time established an internationally unified core set of indicators for evaluating the clinical effectiveness of dental implants, covering the five key areas of the field of dental implants. It is of milestone significance for carrying out standardized clinical diagnosis, treatment, and research on dental implants. The core evaluation indicators determined by this consensus will become an important benchmark for scholars in the field of dental implants worldwide to conduct high-quality research. The consensus is composed of 8 top international experts in the field of oral implantation

Recently, autologous hematopoietic stem cell therapy was completed in Shanghai, and British girls born in the 1990s have suffered from multiple relapses of blood diseases, including stem cells, peripheral blood, and diseases
Recently, autologous hematopoietic stem cell therapy was completed in Shanghai, and British girls born in the 1990s have suffered from multiple relapses of blood diseases, including stem cells, peripheral blood, and diseases

Recently, Catherine, a British girl born in the 1990s, received autologous peripheral blood hematopoietic stem cell transfusion at the Cancer Center of Shanghai Jiahui International Hospital, and was successfully discharged from the warehouse. She is now on her way back to China after being discharged from the hospital. She is also the first patient at Shanghai Jiahui International Hospital to complete relevant treatments. In 2019, Catherine was diagnosed with Hodgkin's lymphoma in the UK, and after treatment, the disease completely improved. During her work and life in China in 2021, she went to seek medical attention due to multiple enlarged lymph nodes. Pathological biopsy confirmed a recurrence of Hodgkin's lymphoma, and through combined targeted drug treatment, her condition was temporarily under control. Last year in the second half of the year, when the disease recurred, the girl began to use immunotherapy combined with targeted drugs for treatment. Expert evaluation suggests that for young patients with hematological tumors, the risk of recurrence is high and treatment difficulty is increasing in the future. Autologous hematopoietic stem cell therapy is recommended