Academician Ge Junbo led this national key laboratory to reveal mechanisms to overcome difficulties. There are 330 million cardiovascular patients in my country.
During the National Science and Technology Activity Week, today, a cardiovascular health science popularization activity organized by the National Key Laboratory of Heart Disease was launched at Zhongshan Hospital Affiliated to Fudan University. News from the event: The "China Cardiovascular Health and Disease Report 2022" shows that the number of patients with cardiovascular disease in my country has reached 330 million, of which 245 million are patients with hypertension, and this number continues to rise. Professor Ge Junbo, academician of the Chinese Academy of Sciences and director of the Department of Cardiology at Zhongshan Hospital, said that the severe situation makes the prevention and treatment of cardiovascular diseases urgent.
It is reported that the National Key Laboratory of Heart Disease was established with the approval of the Ministry of Science and Technology. It is a national key laboratory focusing on clinical and basic translational research of heart disease. It was officially launched at Zhongshan Hospital in February this year. The laboratory has a first-class academic team including Academicians Ge Junbo and Chen Yihan who focus on the field of heart, Academician Huang Hefeng who focuses on the development field, and many national-level outstanding talents. They are responsible for exploring the pathogenesis of heart disease, developing new treatment strategies, and improving public awareness of cardiovascular health. important mission of knowledge.
Ge Junbo metaphorically describes the heart as a complex and sophisticated machine, in which the cardiac conduction system is the "circuit", the coronary artery system is the "oil circuit", and the myocardium and valves are the "body and piston". All of these working together are crucial to maintaining health. It's important. Taking heart valve disease as an example, "If the heart is compared to a room, the valves are four doors. If the door switches are used too much, they will become loose and cannot close properly. This is an inevitable rule, and it is also the reason why the incidence of valvular disease will increase with aging. The reason for the significant increase." Ge Junbo said, "The current promotion and application of transcatheter valve replacement surgery has laid the foundation for the treatment of valvular disease in an aging society. As for the radical treatment of congenital heart valve disease, the simultaneous development of advanced equipment such as thinner and more precise catheters is needed. Follow up promptly.”
Just last year, Academician Ge Junbo's team achieved significant research breakthroughs one after another. The team published a paper in the European Heart Journal. The results of the paper suggest that myocardial ischemia triggers an immune training state in hematopoietic stem cells or monocytes, which can accelerate the progression of atherosclerosis after myocardial ischemia. The team also collaborated with Shanghai Jiao Tong University, Fuwai Hospital of the Chinese Academy of Medical Sciences, and Union Hospital of Fujian Medical University to publish a new technology for plaque vulnerability assessment called "radial wall strain" in the main journal of the Journal of the American College of Cardiology. groundbreaking research. Studies have revealed that assessing plaque vulnerability through vascular RWS can avoid additional invasive procedures and contribute to more accurate prognosis assessment. This discovery is expected to provide a new decision-making model for coronary artery disease risk assessment and optimal management.
Since the establishment of the National Key Laboratory of Cardiology in February this year, certain results have been achieved through a series of high-level research. The expert team has initially revealed the origin of the heart's autonomous rhythm and the working mode of the cardiac transmitter system, providing important clues for understanding the pathogenesis of heart disease. At the same time, we are actively developing innovative drugs, technologies and devices to provide strong support for solving the "stuck" problem in heart disease treatment.
Ge Junbo revealed that in the next step, the laboratory will also be committed to building a research system with a full chain of "industry-university-research" and a full-process "theory-technology-products", striving to obtain the research results on the theory of the origin of heart disease, key technologies and major product research in the next ten years. Breakthroughs can effectively control the high morbidity and mortality of cardiovascular diseases and contribute Chinese wisdom and strength to the development of global cardiovascular health.
At today's science popularization event, experts elaborated on the causes, prevention and treatment methods of cardiovascular diseases through special lectures, case sharing, interactive Q&A, etc., allowing citizens to understand the prevention and treatment of common cardiovascular diseases such as coronary heart disease, hypertension, and heart valve disease. Knowledge has a deeper understanding.
