This company has become the most profitable pharmaceutical enterprise among the world's top 500, relying on COVID-19 Vaccine and Medicine Cominernity | Pfizer | Vaccine

Release time:Apr 14, 2024 13:03 PM

In 2022, Pfizer Pharmaceutical Co., Ltd. became the world's first pharmaceutical company with annual revenue exceeding 100 billion US dollars.

In the latest Fortune Global 500 list released on August 2nd, Pfizer is also the world's most profitable pharmaceutical company, and is listed among the 50 most profitable companies in the Fortune Global 500.

According to reports, in 2022, Pfizer's operating revenue reached 100.33 billion yuan, a year-on-year increase of 23.4%; The profit was 31.372 billion yuan, a year-on-year increase of 42.7%. Both in terms of revenue and profit, Pfizer ranks first in the pharmaceutical industry among the Fortune 500 companies.

Meanwhile, Pfizer ranks 102nd in the Fortune Global 500, an increase of 35 places from the previous year.

This is mainly due to the big sales of Pfizer's COVID-19 vaccine Comirnaty and COVID-19 drug Paxlovid. COVID-19 Vaccine and COVID-19 Oral Medicine have cumulatively contributed more than half of the company's revenue, and the sales revenue will reach 56.739 billion dollars in 2022.

Among the top ten best-selling drugs in the world in 2022, Pfizer's COVID-19 Vaccine Comirnaty will become the "drug king", and its sales will reach 37.81 billion dollars in 2022.

Like Pfizer, MSD also benefited from the sales of COVID-19 Medicine.

Merck is also ranked 231st on the Fortune Global 500, an increase of 31 places from the previous year. In 2022, Merck's operating revenue was $59.283 billion, a year-on-year increase of 15.8%; The profit was 14.519 billion US dollars, a year-on-year increase of 11.3%. In 2022, MSD COVID-19 oral medicine Lagevrio contributed 5.684 billion yuan to the company.


This company has become the most profitable pharmaceutical enterprise among the world's top 500, relying on COVID-19 Vaccine and Medicine Cominernity | Pfizer | Vaccine

However, in 2023, as the COVID-19 weakens and the demand for COVID-19 vaccine and COVID-19 drugs decreases, the income of Pfizer and MSD will decline.

Recently, Pfizer and MSD both disclosed their performance in the 2023 semi annual report.

Data shows that Pfizer's total revenue in the first half of 2023 was 31 billion US dollars, a year-on-year decrease of 42%; Among them, the revenue in the second quarter was 12.7 billion US dollars, a year-on-year decrease of 54%. The overall decline of the company's performance was mainly due to the decline in patient demand for COVID-19 oral drug Paxlovid and COVID-19 vaccine Comirnaty.

Pfizer has also reconfirmed its 2023 performance guidance in this quarter's financial report, consistent with previous plans, with an expected annual revenue of $67 billion to $70 billion.

Merck's total revenue in the first half of 2023 was $29.522 billion, a year-on-year decrease of 3%; The revenue in the second quarter was 15.035 billion US dollars, a year-on-year increase of 3%. The decline in the company's revenue in the first half of the year was mainly due to the sharp decrease in the revenue of COVID-19 drug Lagevrio and the decline in sales of two hypoglycemic drugs.

Currently, Merck's revenue mainly relies on the sales of two major products, PD-1 monoclonal antibody K drug and HPV vaccine, both contributing a total of 16.495 billion US dollars in the first half of 2023.

It is worth noting that the global "medicine king" in 2023 may be replaced by Merck's K-drug. Due to the penetration of early cancer treatment and the huge clinical demand for metastatic cancer, Merck's K-drug sales continued to reach a historic high in the first half of 2023, reaching $12.065 billion, a year-on-year increase of 20%. The market believes that in the second half of the year, K-drug will receive approval decisions for new adjuvant/adjuvant treatments for NSCLC, first-line treatments for HER2 negative and HER2 positive gastric cancer, adjuvant treatments for NSCLC, as well as comprehensive approvals for Merkel cell carcinoma and second-line treatments for hepatocellular carcinoma. The drug's annual sales are expected to reach a new high, and there is no doubt that it will ascend to the throne of "drug king".

Two women were stabbed to death and reported to have committed a crime 4 days before the follow-up visit for schizophrenia. Suspect of a bloody murder case in a Hong Kong shopping mall appeared in court today. Male | Last Friday | Murder case
Two women were stabbed to death and reported to have committed a crime 4 days before the follow-up visit for schizophrenia. Suspect of a bloody murder case in a Hong Kong shopping mall appeared in court today. Male | Last Friday | Murder case

According to Hong Kong's Wen Wei Po, a bloody knife stabbing case occurred at Hollywood Square in Diamond Hill last Friday. The police arrested a 39 year old man on suspicion of stabbing two young women, one of whom was stabbed over 30 times. The suspect appeared in the Kwun Tong Magistrates Court this morning. The police at the Kwun Tong Magistrate's Court temporarily charged the suspect with two counts of murder last Sunday. The suspect appeared in court this morning at the Kwun Tong Magistrate's Court. Acting Chief Magistrate Zheng Jihang, after listening to the opinions of both the prosecution and defense, decided to postpone the hearing for two weeks until 9:30 am on June 19th, waiting for two psychiatric expert reports to be obtained. The defense did not object. Zheng Jihang approved the application, and the defendant needs to be temporarily detained at Xiaolan Mental Hospital. When the suspect appeared in court, he wore black framed glasses, a light gray shirt, and camouflage green shorts, and was able to answer the judge's questions normally. accordingly

Secretary of the Provincial Party Committee: The focus of Henan's "summer harvest" has shifted to agricultural machinery in the northern region of Henan Province. | Support | Science | Organization | Province | Northern Henan | Summer Harvest | Rush Harvest
Secretary of the Provincial Party Committee: The focus of Henan's "summer harvest" has shifted to agricultural machinery in the northern region of Henan Province. | Support | Science | Organization | Province | Northern Henan | Summer Harvest | Rush Harvest

Currently, the highly anticipated summer harvest work in Henan has shifted its focus to the northern region of Henan. According to the Henan Daily client, on June 4th, Lou Yangsheng, Secretary of the Henan Provincial Party Committee, presided over a special video scheduling meeting on the "Three Summers" work in the province, listened to the situation report, analyzed and judged the situation, and arranged and deployed the next steps of work. Governor Wang Kai made specific arrangements. On the evening of May 31, 2023, in Xiafutou Village, Xuliang Town, Boai County, Jiaozuo, Henan Province, villagers braved light rain in the wheat fields to harvest wheat. Visual China Map Lou Yangsheng pointed out that the current summer harvest battle in the province has entered the decisive stage. Doing a good job in summer harvest in northern Henan Province is related to the summer grain yield and seed safety. We should focus on seizing opportunities and make every effort to organize the wheat harvesting work in the northern Henan region, minimize losses, and protect the interests of farmers to the greatest extent possible. Accurate forecasting is essential

Xinhua All Media+| Welcome home! What innovative technologies are protecting the return journey of Shenzhou 15? Spaceship | Shenzhou | Technology
Xinhua All Media+| Welcome home! What innovative technologies are protecting the return journey of Shenzhou 15? Spaceship | Shenzhou | Technology

On June 4th, the return capsule of the Shenzhou-15 manned spacecraft successfully landed at the Dongfeng landing site. Astronauts Fei Junlong, Deng Qingming, and Zhang Lu all safely and smoothly exited the spacecraft, and the Shenzhou-15 manned flight mission was a complete success. What innovative technologies are there to safeguard the return journey of Shenzhou 15 in this mission? On June 4th, the return capsule of the Shenzhou-15 manned spacecraft successfully landed at the Dongfeng landing site. Xinhua News Agency reporter Lian Zhen photographed that "the sky and the ground" ensure the high-precision return of spacecraft. For the Shenzhou series spacecraft, the return and re-entry GNC technology is directly related to the life safety of astronauts. Taking the success of this return mission as a symbol, China has comprehensively upgraded its GNC system since the Shenzhou-12 manned spacecraft, which features autonomous rapid rendezvous and docking, autonomous adaptive prediction and re-entry return guidance, and has completed a comprehensive update and replacement

The Chinese naval fleet has arrived! Assembly | Navy | Chinese Fleet
The Chinese naval fleet has arrived! Assembly | Navy | Chinese Fleet

At noon today, a Chinese naval fleet consisting of Zhanjiang and Xuchang ships arrived at the assembly area of the "Comodo-2023" multinational maritime joint exercise. It is understood that the assembly anchorage for this exercise is 3 nautical miles long and 1.5 nautical miles wide, capable of anchoring up to 50 ships. Naval vessels from various countries participating in the exercise will also arrive at the anchorage today to complete the assembly of the "Komodo 2023" multinational maritime joint exercise, which is held every two years by the Indonesian Navy. This year is already the fourth edition of the exercise. The exercise will be held from June 5th to 8th in the city of Jakarta, South Sulawesi Province, Indonesia, including the port and sea phases. In the coming days, participating navies from various countries will participate in ship reading style search and rescue exercises, maritime interception and damage management exercises, aerial exercises, and other course objectives exercises

New comment: Donkey like "morale" limit pulls US debt "bomb" fuse hard to dismantle US | debt | morale
New comment: Donkey like "morale" limit pulls US debt "bomb" fuse hard to dismantle US | debt | morale

On the evening of June 1st, the US Senate passed a bill on the federal government's debt ceiling and budget, and the flame of the US debt bomb was temporarily extinguished at the last moment. The two parties in the United States have staged an extreme tug of war over the US debt bomb. Some experts believe that the US debt crisis is the result of the reckless politics promoted by the US dollar hegemony, and the underlying cause of this crisis is the highly polarized political system of the US. Since the end of World War II, the US Congress has adjusted the debt ceiling more than a hundred times. The recurring debt crisis will not only have a catastrophic impact on the US economy and people's livelihoods, but also continuously erode the value of US dollar assets such as government credit and US bonds, bringing significant and far-reaching impacts to the global economic landscape. 【