Sudden renal failure! Doctor's reminder: This medicine can be used for up to 3 days in the kidneys | Sir | Doctor

Release time:Apr 13, 2024 21:00 PM

When experiencing fever or abdominal pain

Many people choose to take their own medication for treatment

Recently, a man in Wuhan tried to reduce his fever

Continuous use of antipyretic suppositories for 6 days

Causing acute renal failure

On the morning of the 7th

Mr. Tian, who has been hospitalized for treatment

About to recover and be discharged from the hospital

He deeply regrets mentioning this experience

On May 22nd, Mr. Tian, 68 years old, accompanied his spouse to the community health service center for a physical examination. Thinking of his recent abdominal pain, fever, decreased appetite, and overall fatigue, Mr. Tian also underwent a physical examination. After receiving the test results, he was surprised: creatinine was as high as 600 μ MoI/L is high, 6 times the upper limit of the normal value, and renal failure has occurred.

The family quickly sent Mr. Tian to the nephrology department of Wuhan Fourth Hospital for further examination. The attending doctor inquired in detail and learned that Mr. Tian did not have a history of kidney disease, but a detail mentioned by the elderly person caught the doctor's attention: a week ago, Mr. Tian experienced abdominal pain, diarrhea, and fever. There is a fever reducing suppository at home that not only has a good fever reducing effect, but also has analgesic effects. He used it twice a day for 6 consecutive days. Mr. Tian told the doctor that after taking the medication, the fever subsided at the time, but soon it would start burning again. The doctor determined that Mr. Tian may have suffered from acute kidney failure due to improper use of antipyretic suppositories.

Dr. Song Xiaohong from the Department of Nephrology explained that the antipyretic suppository used by Mr. Tian belongs to the category of nonsteroidal anti-inflammatory drugs. After use, it will inhibit cyclooxygenase and reduce the synthesis of prostaglandins, which are the main vasodilators in the kidneys and can cause renal ischemic damage, leading to acute kidney injury. In addition, his frequent fever, fever reduction, and sweating can also cause hidden fluid loss in the body, exacerbating renal ischemia. In addition, his prolonged use of medication resulted in drug accumulation in the kidneys, leading to drug-induced kidney injury. After hospitalization, medical staff provided Mr. Tian with treatment such as anti infection, kidney protection, and alkaline urine. His condition quickly improved.

It is understood that there are a large family of non steroidal anti-inflammatory drugs, including more than 20 types, including aspirin, indomethacin, naproxen, naproxen, diclofenac, ibuprofen, nimesulide, rofecoxib, celecoxib, phenacetin, acetaminophen, prednisone, indomethacin, antipyrine, aminopyrine, etc. Many citizens like to use this type of medication on their own when experiencing fever and pain.

Reminder from Song Xiaohong:

Non steroidal anti-inflammatory drugs have the risk of causing acute kidney function damage, gastrointestinal bleeding, and other complications. When used to reduce fever, it is best not to exceed 3 days. When recurrent fever occurs, the cause must be identified before targeted medication is taken.

In addition, improper use of common medicines such as cold medicine, antibiotics, and stomach medicine in daily life can also lead to acute kidney failure. When using such drugs, it is necessary to take them under the guidance of a doctor and not self overdose. People with kidney disease should be more cautious when using painkillers.

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