A pneumoconiosis patient completed a lung transplant surgery in Ruijin and was reborn, rushing to the outside world for over 2000 kilometers to expel pneumoconiosis

Release time:Apr 15, 2024 04:16 AM

When I saw Mr. Wang, he was standing by the window breathing fresh air. It was the third day after his lung transplant surgery. As a recipient of the "Guangju Shanai" Organ Transplantation Special Charity Fund at Ruijin Hospital affiliated with Shanghai Jiao Tong University School of Medicine, Mr. Wang successfully performed a right lung transplant surgery. "I never expected the recovery to be so fast, so good!" His wife choked up and said, "Thank you to Ruijin Hospital, thank you to Director Li and the doctors and nurses!"

Repeated coughing and wheezing, unable to get up, and terminal stage pneumoconiosis with limited vitality

"When I'm feeling unwell, I keep coughing and panting, and it's difficult and painful to walk and sleep. Many people in our hometown passed away due to this disease at a young age." Looking back on his seriously ill days, Mr. Wang felt like a nightmare.

Mr. Wang, 44 years old, has been engaged in granite related work for more than 20 years. He has been in direct contact with dust all year round and has weak protection awareness. He has not worn a mask. Starting from 2021, he experienced difficulty breathing and gradually worsened. After the Spring Festival this year, he was unable to engage in general physical activities, with severe chest tightness and pain. Despite visiting multiple hospitals, his symptoms continued to recur until he was unable to undergo deoxygenation. Through the introduction of family and friends, Mr. Wang, who was no longer able to get up, drove from Yunnan to Ruijin Hospital for 2 days to seek medical treatment, hoping to find vitality.

Upon admission examination, it was found that Mr. Wang's blood oxygen saturation was below 90% during oxygen inhalation. Chest CT scan shows pneumothorax on the right side, multiple patchy, nodular, and nodular shadows in both lungs, bullous lesions in the left lung, widened pulmonary arteries, enlarged mediastinum and bilateral hilar lymph nodes. The diagnosis is end-stage pneumoconiosis. If not treated immediately, the patient is highly likely to die from respiratory failure. Lung transplantation surgery has become the only and effective treatment option.

"Lung transplantation is a highly challenging surgery in the field of thoracic surgery, and can also be said to be the most challenging among all organ transplants. The lungs are directly connected to the atmosphere, and external microorganisms can increase the risk of infection in the transplanted lungs. The difficulty of the surgery itself and issues such as postoperative infection control and rejection reactions are more risky than other organ transplants," explained Li Hecheng, director of thoracic surgery. Before the surgery, the lung transplantation team actively improved the examination, developed a personalized diagnosis and treatment plan for Mr. Wang, and carried out rescue measures such as respiratory nebulization and pneumothorax treatment to ensure that everything was safe and sound; At the same time, organize multidisciplinary consultations in departments such as Respiratory and Critical Care Medicine, Anesthesiology, Critical Care Medicine, Nutrition, and Rehabilitation, develop detailed surgical plans and postoperative management plans, wait for lung source, and prepare for surgery at any time.

 


A pneumoconiosis patient completed a lung transplant surgery in Ruijin and was reborn, rushing to the outside world for over 2000 kilometers to expel pneumoconiosis

Multidisciplinary support and escort, lung transplantation surgery saves lives

Multidisciplinary support and escort, lung transplantation surgery saves lives

On June 23rd, thanking the donors for their great love, Mr. Wang and others came to donate their lungs with love. The ischemic time requirement for lung transplantation surgery is short, and the optimal "preservation period" is only 6 hours. A longer ischemic time can lead to a decrease in the quality of the donor lung, affecting the transplantation effect. This is a life relay surgery that races against time. Therefore, upon receiving the information, Li Hecheng immediately initiated a contingency plan to arrange patients, obtain donors, and coordinate surgeries; Dr. Du Hailei and Dr. Xing Lei, the hospital's OPO specialist, quickly rushed to Guangxi and tirelessly retrieved this precious right lung.

Open chest, remove diseased lung, implant donor lung, suture pulmonary artery, flush chest cavity Li Hecheng personally operated the surgery and led the lung transplant team to collaborate with the anesthesia, transfusion, and operating room teams. After more than 4 hours, the surgery was successfully completed, accompanied by fresh lungs opening and closing in the chest cavity.

24 hours after surgery, Mr. Wang successfully removed the tracheal intubation and on the third day after surgery, he was transferred back to the general ward from the intensive care unit. Surgical treatment is the first step, and after successful transplantation, patients still need to overcome difficulties such as postoperative infection and rejection. Postoperative sputum aspiration under bronchoscopy, infection control, nutritional support, blood sugar control Combining multiple disciplines, Mr. Wang's every treatment is well-organized, and postoperative infections and rejection are well controlled. "In addition to interdisciplinary cooperation, considering the patient's financial difficulties, we have specifically contacted the Guangju Shan'ai Charity Fund for assistance, and also contacted doctors from Yunnan who came to Ruijin for further education. We will continue to guide and monitor the patient's treatment after discharge and return home, and do our best to ensure the patient's speedy recovery." Li Hecheng introduced.

"Thank you, it feels like a dream." Mr. Wang kept saying "thank you" to the medical staff with gratitude. From terminal stage pneumoconiosis to successful transplantation, Mr. Wang has now been discharged smoothly.

Why is "Cancer King" immunotherapy ineffective? Fudan Cancer Hospital Reveals New Mechanisms of Immunosuppressive Environment for pancreatic cancer CRIP1 | Tumor | pancreatic cancer
Why is "Cancer King" immunotherapy ineffective? Fudan Cancer Hospital Reveals New Mechanisms of Immunosuppressive Environment for pancreatic cancer CRIP1 | Tumor | pancreatic cancer

Immunotherapy has been proven to achieve significant therapeutic effects in various solid tumors. However, for pancreatic cancer, known as the "king of cancer", immunotherapy has been ineffective. On August 4, Professor Yu Xianjun, Dean of the Cancer Hospital Affiliated to Fudan University, and Shi Si, Associate Professor of Pancreatic Surgery released a research achievement, which first found the key role of cysteine rich protein 1 in shaping the immunosuppressive microenvironment of pancreatic cancer, filled the gap in the research field of immunosuppressive microenvironment of pancreatic cancer, and provided a theoretical basis for precise immunotherapy of pancreatic cancer patients. Ductal adenocarcinoma of the pancreas is the main type of pancreatic cancer, accounting for about 90% of all pancreatic cancer. Due to its high malignancy and poor treatment effectiveness, pancreatic ductal adenocarcinoma has always been one of the most malignant tumors. In recent years, the level of surgical techniques and comprehensive treatment has been achieved

A 14-year-old girl suffers from a rare eye disease and receives support from a public welfare fund. Symptoms of "I haven't looked in the mirror for a long time" | Patient | Public welfare
A 14-year-old girl suffers from a rare eye disease and receives support from a public welfare fund. Symptoms of "I haven't looked in the mirror for a long time" | Patient | Public welfare

A 14-year-old girl has been experiencing symptoms such as protruding pupils, incomplete eye closure, corneal injury, restricted eye movement, and overall fatigue for several years. The physical discomfort and facial abnormalities caused by eye diseases have made her increasingly reticent, and her temperament is vastly different from before. At the Ophthalmology Department of the Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, the pupil has been diagnosed with a rare thyroid ophthalmopathy combined with myasthenia gravis, which requires prompt treatment. However, considering the young age of the pupil, conventional hormone and radiation therapy cannot be used. Therefore, Zhou Huifang, Deputy Director of Ophthalmology and thyroid ophthalmology expert, has developed a targeted drug combined with surgical treatment plan for it, and targeted drug treatment will be performed first. Three months ago, I was hospitalized for one week with mydriasis and received intravenous targeted drug treatment. Afterwards, I went home for observation and followed up on time

The municipal eye disease prevention and treatment center launched the dry eye diagnosis and treatment studio, and the incidence rate of dry eye in China is about 21% to 30% of the meibomian gland | dry eye | eye disease
The municipal eye disease prevention and treatment center launched the dry eye diagnosis and treatment studio, and the incidence rate of dry eye in China is about 21% to 30% of the meibomian gland | dry eye | eye disease

According to the Statistics of Chinese Dry Eye Expert Consensus, the incidence rate of dry eye in China is about 21%~30%, and it is estimated that there are at least 300 million patients nationwide. The Dry Eye Diagnosis and Treatment Studio of Shanghai Eye Disease Prevention and Treatment Center was officially launched today. In the future, the studio will continuously improve the dry eye diagnosis and treatment standards, and form standardized diagnosis and treatment concepts and service models. Suitable technologies will be promoted to the community, allowing residents to enjoy convenient dry eye diagnosis and treatment services at their doorstep. Executive Dean and Party Secretary Gao Wei stated that this is also one of the livelihood service measures recently launched by the hospital around high-quality development and meeting the needs of the people. It is reported that dry eye syndrome is a chronic ocular surface disease caused by multiple factors. The instability of the tear film or imbalance of the ocular surface microenvironment caused by abnormal quality, quantity, and dynamics of tears can be accompanied by ocular surface inflammatory reactions, tissue damage, and nerve abnormalities, resulting in various discomforts in the eyes

The Ninth Hospital has taken the lead in formulating the world's first consensus on core indicators for clinical evaluation of dental implants, which has been officially published in clinical practice
The Ninth Hospital has taken the lead in formulating the world's first consensus on core indicators for clinical evaluation of dental implants, which has been officially published in clinical practice

The International Dental Implant Consensus Report, jointly written by the Ninth People's Hospital affiliated with Shanghai Jiao Tong University School of Medicine and renowned universities in the field of dentistry such as Harvard University, University of Zurich, University of Gothenburg, Columbia University, and University of Frankfurt, has recently been jointly published in top journals in the field of dentistry, including Clinical Periodontology and Clinical Dental Implant Research. This consensus has for the first time established an internationally unified core set of indicators for evaluating the clinical effectiveness of dental implants, covering the five key areas of the field of dental implants. It is of milestone significance for carrying out standardized clinical diagnosis, treatment, and research on dental implants. The core evaluation indicators determined by this consensus will become an important benchmark for scholars in the field of dental implants worldwide to conduct high-quality research. The consensus is composed of 8 top international experts in the field of oral implantation

Recently, autologous hematopoietic stem cell therapy was completed in Shanghai, and British girls born in the 1990s have suffered from multiple relapses of blood diseases, including stem cells, peripheral blood, and diseases
Recently, autologous hematopoietic stem cell therapy was completed in Shanghai, and British girls born in the 1990s have suffered from multiple relapses of blood diseases, including stem cells, peripheral blood, and diseases

Recently, Catherine, a British girl born in the 1990s, received autologous peripheral blood hematopoietic stem cell transfusion at the Cancer Center of Shanghai Jiahui International Hospital, and was successfully discharged from the warehouse. She is now on her way back to China after being discharged from the hospital. She is also the first patient at Shanghai Jiahui International Hospital to complete relevant treatments. In 2019, Catherine was diagnosed with Hodgkin's lymphoma in the UK, and after treatment, the disease completely improved. During her work and life in China in 2021, she went to seek medical attention due to multiple enlarged lymph nodes. Pathological biopsy confirmed a recurrence of Hodgkin's lymphoma, and through combined targeted drug treatment, her condition was temporarily under control. Last year in the second half of the year, when the disease recurred, the girl began to use immunotherapy combined with targeted drugs for treatment. Expert evaluation suggests that for young patients with hematological tumors, the risk of recurrence is high and treatment difficulty is increasing in the future. Autologous hematopoietic stem cell therapy is recommended