Zhongshan Hospital's heart transplant technique is bold and saves lives. A 17-year-old boy is in critical condition for fulminant severe myocarditis. Transplantation surgery | Heart | Myocarditis

Release time:Apr 13, 2024 23:07 PM

A 17-year-old boy had a sudden cardiac arrest and underwent cardiopulmonary resuscitation for two hours. After circling through the gates of hell, a team of experts from the Department of Cardiology at Zhongshan Hospital affiliated with Fudan University bravely broke through the restricted area and saved his life through heart transplantation. The patient's various indicators improved after surgery and was discharged smoothly on the 23rd.

Xiaoye is a high school sophomore student who began experiencing symptoms such as fever and vomiting in late April, and subsequently experienced a series of symptoms such as general fatigue, chest tightness, and chest pain. During the process of seeking medical treatment at the local hospital, Xiaoye experienced sudden respiratory and cardiac arrest, and was urgently implanted with ECMO before being transferred to the ICU for further treatment.

Preliminary diagnosis: Xiaoye suffers from fulminant severe myocarditis. Outbreaking severe myocarditis is one of the most severe and special clinical types of myocarditis, with a rapid onset and extremely rapid progression. If left untreated, malignant arrhythmias, acute severe heart failure, and extremely high mortality rates can occur in the early stages. After 11 days of ECMO treatment, there was no significant improvement in the heart function of the lobules, and complications such as infection and acute renal failure occurred one after another. Life is on the line, and life and death are at stake.

On the late night of May 5th, an ambulance carrying Xiaoye rushed to Zhongshan Hospital. Originally, with the last glimmer of hope, the family of Xiaoye came to seek help from Professor Wang Chunsheng, a renowned expert in Chinese cardiology. After fully understanding Xiaoye's condition, Professor Wang judged that Xiaoye's current condition is extremely critical, and early heart transplantation is his only hope for survival.


Zhongshan Hospital's heart transplant technique is bold and saves lives. A 17-year-old boy is in critical condition for fulminant severe myocarditis. Transplantation surgery | Heart | Myocarditis

Considering the patient's young age, even a heart transplant carries enormous surgical risks, Wang Chunsheng decided to fight for the last glimmer of opportunity for him. Dr. Yang Zhaohua, Deputy Chief Physician of the Heart Transplantation Team, immediately communicated with the local hospital, carefully formulated a cross provincial transportation plan, and made full preparations for various potential risks that may occur during the transportation process.

That night, Xiaoye was successfully transferred to the intensive care unit of the cardiology department. The examination shows that the severity of the lobular condition far exceeds expectations, with not only heart failure and renal failure, but also severe pulmonary infections, as well as various complications such as systemic coagulation dysfunction and gastrointestinal bleeding, which can be life-threatening at any time. ECMO+IABP+CRRT+ventilator... almost all life support methods in the intensive care unit are used, and only suitable heart transplant can truly relieve the life crisis.

Fortunately, the national organ allocation waiting system received good news: Xiaoye was quickly allocated to a matching heart. The next morning, doctors Yang Zhaohua, Liu Dingqian, and Yin Xiujie from the cardiology department rushed to the hospital where the heart donor was located with equipment. At 3pm, the donor acquisition was successfully completed and they immediately rushed back to Zhongshan Hospital. The operating room had already made sufficient preoperative preparations, and as soon as the heart supply arrived, Professor Wang Chunsheng immediately led the team to start the heart transplant surgery. After more than 5 hours of fierce competition, the heart transplant surgery was successfully completed, and Xiaoye successfully escaped the assistance of ECMO and IABP. A healthy heart resumed beating in his chest cavity.

After the surgery, under the careful care of the intensive care unit of the cardiac surgery department, Xiaoye successively overcame important obstacles in transplantation surgery such as acute rejection, infection, and malnutrition, and gradually recovered various severely damaged physical functions. 14 days after surgery, the renal function of the lobules returned to normal and no longer relied on hemodialysis treatment; 20 days after surgery, Xiaoye successfully withdrew from the ventilator; One month after surgery, Xiaoye was transferred from the cardiology intensive care unit to the general ward. Not long ago, the small lobe recovered well after surgery, and all indicators improved, and it was discharged smoothly.


Zhongshan Hospital's heart transplant technique is bold and saves lives. A 17-year-old boy is in critical condition for fulminant severe myocarditis. Transplantation surgery | Heart | Myocarditis

The reporter learned that since carrying out heart transplantation in 2000, Zhongshan Hospital has undergone more than 20 years of development under the leadership of Professor Wang Chunsheng, and has completed more than 600 heart transplant surgeries, ranking among the top in terms of the number and effectiveness of surgeries in the country. The postoperative survival rate of heart transplant patients is increasing. "As long as patients have 1% hope, we must make 100% effort, because we carry the trust of life!" Professor Wang Chunsheng said.

Why is "Cancer King" immunotherapy ineffective? Fudan Cancer Hospital Reveals New Mechanisms of Immunosuppressive Environment for pancreatic cancer CRIP1 | Tumor | pancreatic cancer
Why is "Cancer King" immunotherapy ineffective? Fudan Cancer Hospital Reveals New Mechanisms of Immunosuppressive Environment for pancreatic cancer CRIP1 | Tumor | pancreatic cancer

Immunotherapy has been proven to achieve significant therapeutic effects in various solid tumors. However, for pancreatic cancer, known as the "king of cancer", immunotherapy has been ineffective. On August 4, Professor Yu Xianjun, Dean of the Cancer Hospital Affiliated to Fudan University, and Shi Si, Associate Professor of Pancreatic Surgery released a research achievement, which first found the key role of cysteine rich protein 1 in shaping the immunosuppressive microenvironment of pancreatic cancer, filled the gap in the research field of immunosuppressive microenvironment of pancreatic cancer, and provided a theoretical basis for precise immunotherapy of pancreatic cancer patients. Ductal adenocarcinoma of the pancreas is the main type of pancreatic cancer, accounting for about 90% of all pancreatic cancer. Due to its high malignancy and poor treatment effectiveness, pancreatic ductal adenocarcinoma has always been one of the most malignant tumors. In recent years, the level of surgical techniques and comprehensive treatment has been achieved

A 14-year-old girl suffers from a rare eye disease and receives support from a public welfare fund. Symptoms of "I haven't looked in the mirror for a long time" | Patient | Public welfare
A 14-year-old girl suffers from a rare eye disease and receives support from a public welfare fund. Symptoms of "I haven't looked in the mirror for a long time" | Patient | Public welfare

A 14-year-old girl has been experiencing symptoms such as protruding pupils, incomplete eye closure, corneal injury, restricted eye movement, and overall fatigue for several years. The physical discomfort and facial abnormalities caused by eye diseases have made her increasingly reticent, and her temperament is vastly different from before. At the Ophthalmology Department of the Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, the pupil has been diagnosed with a rare thyroid ophthalmopathy combined with myasthenia gravis, which requires prompt treatment. However, considering the young age of the pupil, conventional hormone and radiation therapy cannot be used. Therefore, Zhou Huifang, Deputy Director of Ophthalmology and thyroid ophthalmology expert, has developed a targeted drug combined with surgical treatment plan for it, and targeted drug treatment will be performed first. Three months ago, I was hospitalized for one week with mydriasis and received intravenous targeted drug treatment. Afterwards, I went home for observation and followed up on time

The municipal eye disease prevention and treatment center launched the dry eye diagnosis and treatment studio, and the incidence rate of dry eye in China is about 21% to 30% of the meibomian gland | dry eye | eye disease
The municipal eye disease prevention and treatment center launched the dry eye diagnosis and treatment studio, and the incidence rate of dry eye in China is about 21% to 30% of the meibomian gland | dry eye | eye disease

According to the Statistics of Chinese Dry Eye Expert Consensus, the incidence rate of dry eye in China is about 21%~30%, and it is estimated that there are at least 300 million patients nationwide. The Dry Eye Diagnosis and Treatment Studio of Shanghai Eye Disease Prevention and Treatment Center was officially launched today. In the future, the studio will continuously improve the dry eye diagnosis and treatment standards, and form standardized diagnosis and treatment concepts and service models. Suitable technologies will be promoted to the community, allowing residents to enjoy convenient dry eye diagnosis and treatment services at their doorstep. Executive Dean and Party Secretary Gao Wei stated that this is also one of the livelihood service measures recently launched by the hospital around high-quality development and meeting the needs of the people. It is reported that dry eye syndrome is a chronic ocular surface disease caused by multiple factors. The instability of the tear film or imbalance of the ocular surface microenvironment caused by abnormal quality, quantity, and dynamics of tears can be accompanied by ocular surface inflammatory reactions, tissue damage, and nerve abnormalities, resulting in various discomforts in the eyes

The Ninth Hospital has taken the lead in formulating the world's first consensus on core indicators for clinical evaluation of dental implants, which has been officially published in clinical practice
The Ninth Hospital has taken the lead in formulating the world's first consensus on core indicators for clinical evaluation of dental implants, which has been officially published in clinical practice

The International Dental Implant Consensus Report, jointly written by the Ninth People's Hospital affiliated with Shanghai Jiao Tong University School of Medicine and renowned universities in the field of dentistry such as Harvard University, University of Zurich, University of Gothenburg, Columbia University, and University of Frankfurt, has recently been jointly published in top journals in the field of dentistry, including Clinical Periodontology and Clinical Dental Implant Research. This consensus has for the first time established an internationally unified core set of indicators for evaluating the clinical effectiveness of dental implants, covering the five key areas of the field of dental implants. It is of milestone significance for carrying out standardized clinical diagnosis, treatment, and research on dental implants. The core evaluation indicators determined by this consensus will become an important benchmark for scholars in the field of dental implants worldwide to conduct high-quality research. The consensus is composed of 8 top international experts in the field of oral implantation

Recently, autologous hematopoietic stem cell therapy was completed in Shanghai, and British girls born in the 1990s have suffered from multiple relapses of blood diseases, including stem cells, peripheral blood, and diseases
Recently, autologous hematopoietic stem cell therapy was completed in Shanghai, and British girls born in the 1990s have suffered from multiple relapses of blood diseases, including stem cells, peripheral blood, and diseases

Recently, Catherine, a British girl born in the 1990s, received autologous peripheral blood hematopoietic stem cell transfusion at the Cancer Center of Shanghai Jiahui International Hospital, and was successfully discharged from the warehouse. She is now on her way back to China after being discharged from the hospital. She is also the first patient at Shanghai Jiahui International Hospital to complete relevant treatments. In 2019, Catherine was diagnosed with Hodgkin's lymphoma in the UK, and after treatment, the disease completely improved. During her work and life in China in 2021, she went to seek medical attention due to multiple enlarged lymph nodes. Pathological biopsy confirmed a recurrence of Hodgkin's lymphoma, and through combined targeted drug treatment, her condition was temporarily under control. Last year in the second half of the year, when the disease recurred, the girl began to use immunotherapy combined with targeted drugs for treatment. Expert evaluation suggests that for young patients with hematological tumors, the risk of recurrence is high and treatment difficulty is increasing in the future. Autologous hematopoietic stem cell therapy is recommended