Zhongshan Hospital collaborates with multiple disciplines to reshape the patient's "life channel". The elderly in their seventies have difficulty eating for six months and have lost 30 pounds due to severe weight loss. The diverticulum | esophagus | discipline

Release time:Apr 15, 2024 08:25 AM

"Did Aunt Qi drink Congee this morning? How much did she drink? Did she vomit?". This means that the "eating difficulties" that have troubled Aunt Qi for over a decade have finally been resolved, and she can now be discharged smoothly. Aunt Qi held the hands of Professor Zhang Shuncai and Professor Zhou Pinghong, constantly thanking them, "Thank you to the doctors at Zhongshan Hospital. You are so amazing, I can finally eat smoothly!"

72 year old Aunt Qi suffers from extremely severe congenital scoliosis, with a scoliosis angle of nearly 70 degrees and a height of only 115cm. For over a decade, I have been suffering from long-term throat pain and vomiting when eating. In the local area, I was diagnosed with "pharyngoesophageal diverticulum", which is a pocket like substance growing at the entrance of Aunt Qi's upper esophagus, causing most of the food to slide into the pocket and cause vomiting.

Two years ago, due to worsening symptoms, Aunt Qi placed two esophageal stents in the local hospital. But the postoperative condition did not improve. In the past six months, not only did he have difficulty eating, but he even vomited when drinking water, and he also developed pneumonia multiple times. Even though the symptoms did not improve after removing a stent in the local hospital, Aunt Qi's inability to eat normally for a long time caused her to lose over 30 pounds, which is less than 60 pounds.

Afterwards, Aunt Qi traveled to multiple hospitals across the country and was refused requests for further treatment due to the difficulty and high risk of the surgery. Upon recommendation, Aunt Qi, holding the last glimmer of hope, came to Professor Zhang Shuncai's outpatient clinic in the Department of Gastroenterology at Zhongshan Hospital affiliated with Fudan University.


Zhongshan Hospital collaborates with multiple disciplines to reshape the patient's "life channel". The elderly in their seventies have difficulty eating for six months and have lost 30 pounds due to severe weight loss. The diverticulum | esophagus | discipline

Due to his unique physique and incomplete medical history, Professor Zhang, who has always been known for treating difficult and severe cases, has made a mistake this time. "As long as my mother can drink Congee, it's OK." In the face of such a basic demand, Professor Zhang Shuncai has strengthened his determination to treat patients. After admitting Aunt Qi to the hospital, Deputy Chief Physician Zhang Ningping and the digestive department's diagnosis and treatment team first strengthened anti infection and nutritional support treatment, quickly improved various examinations, and consulted with the Endoscopy Center and Anesthesiology Department for discussion. Finally, it was decided to try gastroscopic esophageal stent removal under rapid general anesthesia tracheal intubation in a lateral position.

On August 17th, through careful intraoperative exploration, it was found that Aunt Qi's esophageal pouch did not shrink, but instead grew significantly larger due to food accumulation, with a diameter of 2.5 centimeters and a maximum diameter of 4.3 centimeters. The stent, which had been inserted for two years, not only failed to function properly and covered the cavity of the diverticulum, but also embedded one end into the esophageal wall. granulation, scars, and the metal wire of the stent were inseparable and filled with food that could not be removed, making the originally narrow esophagus even more congested. In addition, the "bag mouth" of the diverticulum is close to the trachea, and the blocked spilled food will flow into the trachea, leading to Aunt Qi's previous repeated pneumonia. If not handled in a timely manner, the diverticulum will further enlarge, leading to perforation and bleeding, and the consequences are unimaginable. Conventional surgical methods cannot simultaneously separate the stent and solve the problem of the pouch, and the situation is even more complex than expected.

Dr. Ma Lili, the chief surgeon, reported this special case to Professor Zhou Pinghong, the director of the Endoscopy Center. Professor Zhou Pinghong, who was eating in the office, put down his chopsticks and immediately rushed to the operating room. After learning about the current surgical situation, he decided to try using a cutting knife to cut thick scars along the stent, separating the stent from the esophagus, which greatly tested the doctor's precise operation and team cooperation. Any slight carelessness during surgery may lead to esophageal perforation, which in turn can cause serious infections and even endanger life.

Foreign physicians from countries such as Egypt, Jordan, and Portugal who are currently studying at endoscopy centers have also heard of this and come to observe. Half an hour later, a metal tube with a length of 15 centimeters and a diameter of 1.8 centimeters was successfully peeled off and removed.


Zhongshan Hospital collaborates with multiple disciplines to reshape the patient's "life channel". The elderly in their seventies have difficulty eating for six months and have lost 30 pounds due to severe weight loss. The diverticulum | esophagus | discipline

After inspecting the esophageal wound and the condition of the esophageal diverticulum sac, Professor Zhou decided to use the latest tunneling technique - endoscopic submucosal tunnel diverticulum isolation surgery to help Aunt Qi cut open this "bag" and completely solve the problem of eating difficulties that Aunt Qi has been troubled by for more than ten years.

The STESD surgery involves establishing a submucosal tunnel in the esophagus, separating it into the spinal space between the esophageal diverticula, and performing a spinal incision within the tunnel. Enable the content to be unobstructed as the inter spinal resistance decreases. But Aunt Qi's severe scoliosis of the spine is S-shaped, and her esophagus is also severely twisted. In addition, the location of the diverticulum is special, making it difficult to build a tunnel like walking a steel wire. When the last metal clip for suturing the wound closed, applause erupted in the operating room, not only praising Professor Zhou's superb skills, but also genuinely bringing joy to the patient. "The love of doctors is also reflected in the continuous innovative practice of relieving the pain of patients. It is closely intertwined with the filial piety of children and the hope of patients," said Professor Zhou Pinghong.

After the operation, under the careful care of the digestive medical team, Aunt Qi recovered well, pulled out the gastrointestinal decompression tube the next day, and could have Congee the third day.

As the first comprehensive national medical center approved in the country, Zhongshan Hospital affiliated with Fudan University focuses on key core technical issues such as "one step at the door" and "bottleneck" that meet the health needs of the people. The STESD surgery performed by Professor Zhou Pinghong is a new minimally invasive endoscopic treatment technology pioneered internationally by the Endoscopy Center of Zhongshan Hospital. Since 2016, nearly a hundred cases have been successfully implemented and continuously promoted both domestically and internationally.


Zhongshan Hospital collaborates with multiple disciplines to reshape the patient's "life channel". The elderly in their seventies have difficulty eating for six months and have lost 30 pounds due to severe weight loss. The diverticulum | esophagus | discipline
Why is "Cancer King" immunotherapy ineffective? Fudan Cancer Hospital Reveals New Mechanisms of Immunosuppressive Environment for pancreatic cancer CRIP1 | Tumor | pancreatic cancer
Why is "Cancer King" immunotherapy ineffective? Fudan Cancer Hospital Reveals New Mechanisms of Immunosuppressive Environment for pancreatic cancer CRIP1 | Tumor | pancreatic cancer

Immunotherapy has been proven to achieve significant therapeutic effects in various solid tumors. However, for pancreatic cancer, known as the "king of cancer", immunotherapy has been ineffective. On August 4, Professor Yu Xianjun, Dean of the Cancer Hospital Affiliated to Fudan University, and Shi Si, Associate Professor of Pancreatic Surgery released a research achievement, which first found the key role of cysteine rich protein 1 in shaping the immunosuppressive microenvironment of pancreatic cancer, filled the gap in the research field of immunosuppressive microenvironment of pancreatic cancer, and provided a theoretical basis for precise immunotherapy of pancreatic cancer patients. Ductal adenocarcinoma of the pancreas is the main type of pancreatic cancer, accounting for about 90% of all pancreatic cancer. Due to its high malignancy and poor treatment effectiveness, pancreatic ductal adenocarcinoma has always been one of the most malignant tumors. In recent years, the level of surgical techniques and comprehensive treatment has been achieved

A 14-year-old girl suffers from a rare eye disease and receives support from a public welfare fund. Symptoms of "I haven't looked in the mirror for a long time" | Patient | Public welfare
A 14-year-old girl suffers from a rare eye disease and receives support from a public welfare fund. Symptoms of "I haven't looked in the mirror for a long time" | Patient | Public welfare

A 14-year-old girl has been experiencing symptoms such as protruding pupils, incomplete eye closure, corneal injury, restricted eye movement, and overall fatigue for several years. The physical discomfort and facial abnormalities caused by eye diseases have made her increasingly reticent, and her temperament is vastly different from before. At the Ophthalmology Department of the Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, the pupil has been diagnosed with a rare thyroid ophthalmopathy combined with myasthenia gravis, which requires prompt treatment. However, considering the young age of the pupil, conventional hormone and radiation therapy cannot be used. Therefore, Zhou Huifang, Deputy Director of Ophthalmology and thyroid ophthalmology expert, has developed a targeted drug combined with surgical treatment plan for it, and targeted drug treatment will be performed first. Three months ago, I was hospitalized for one week with mydriasis and received intravenous targeted drug treatment. Afterwards, I went home for observation and followed up on time

The municipal eye disease prevention and treatment center launched the dry eye diagnosis and treatment studio, and the incidence rate of dry eye in China is about 21% to 30% of the meibomian gland | dry eye | eye disease
The municipal eye disease prevention and treatment center launched the dry eye diagnosis and treatment studio, and the incidence rate of dry eye in China is about 21% to 30% of the meibomian gland | dry eye | eye disease

According to the Statistics of Chinese Dry Eye Expert Consensus, the incidence rate of dry eye in China is about 21%~30%, and it is estimated that there are at least 300 million patients nationwide. The Dry Eye Diagnosis and Treatment Studio of Shanghai Eye Disease Prevention and Treatment Center was officially launched today. In the future, the studio will continuously improve the dry eye diagnosis and treatment standards, and form standardized diagnosis and treatment concepts and service models. Suitable technologies will be promoted to the community, allowing residents to enjoy convenient dry eye diagnosis and treatment services at their doorstep. Executive Dean and Party Secretary Gao Wei stated that this is also one of the livelihood service measures recently launched by the hospital around high-quality development and meeting the needs of the people. It is reported that dry eye syndrome is a chronic ocular surface disease caused by multiple factors. The instability of the tear film or imbalance of the ocular surface microenvironment caused by abnormal quality, quantity, and dynamics of tears can be accompanied by ocular surface inflammatory reactions, tissue damage, and nerve abnormalities, resulting in various discomforts in the eyes

The Ninth Hospital has taken the lead in formulating the world's first consensus on core indicators for clinical evaluation of dental implants, which has been officially published in clinical practice
The Ninth Hospital has taken the lead in formulating the world's first consensus on core indicators for clinical evaluation of dental implants, which has been officially published in clinical practice

The International Dental Implant Consensus Report, jointly written by the Ninth People's Hospital affiliated with Shanghai Jiao Tong University School of Medicine and renowned universities in the field of dentistry such as Harvard University, University of Zurich, University of Gothenburg, Columbia University, and University of Frankfurt, has recently been jointly published in top journals in the field of dentistry, including Clinical Periodontology and Clinical Dental Implant Research. This consensus has for the first time established an internationally unified core set of indicators for evaluating the clinical effectiveness of dental implants, covering the five key areas of the field of dental implants. It is of milestone significance for carrying out standardized clinical diagnosis, treatment, and research on dental implants. The core evaluation indicators determined by this consensus will become an important benchmark for scholars in the field of dental implants worldwide to conduct high-quality research. The consensus is composed of 8 top international experts in the field of oral implantation

Recently, autologous hematopoietic stem cell therapy was completed in Shanghai, and British girls born in the 1990s have suffered from multiple relapses of blood diseases, including stem cells, peripheral blood, and diseases
Recently, autologous hematopoietic stem cell therapy was completed in Shanghai, and British girls born in the 1990s have suffered from multiple relapses of blood diseases, including stem cells, peripheral blood, and diseases

Recently, Catherine, a British girl born in the 1990s, received autologous peripheral blood hematopoietic stem cell transfusion at the Cancer Center of Shanghai Jiahui International Hospital, and was successfully discharged from the warehouse. She is now on her way back to China after being discharged from the hospital. She is also the first patient at Shanghai Jiahui International Hospital to complete relevant treatments. In 2019, Catherine was diagnosed with Hodgkin's lymphoma in the UK, and after treatment, the disease completely improved. During her work and life in China in 2021, she went to seek medical attention due to multiple enlarged lymph nodes. Pathological biopsy confirmed a recurrence of Hodgkin's lymphoma, and through combined targeted drug treatment, her condition was temporarily under control. Last year in the second half of the year, when the disease recurred, the girl began to use immunotherapy combined with targeted drugs for treatment. Expert evaluation suggests that for young patients with hematological tumors, the risk of recurrence is high and treatment difficulty is increasing in the future. Autologous hematopoietic stem cell therapy is recommended