Unexpectedly, the internal organs have come out! The multidisciplinary team of Zhongshan Hospital successfully dismantled the bomb, and the grandfather's abdomen was as huge as a pregnancy in October. Surgery | blood vessels | viscera

Release time:Apr 14, 2024 02:31 AM

The abdomen is huge like being pregnant for ten months, with skin ulcers and rags on the raised area of the belly. Underneath the thin skin are faintly visible internal organs, which look like a "big ball" about to explode... When Mr. Luan came to Zhongshan Hospital affiliated with Fudan University for consultation, Professor Dong Zhihui of the Department of Vascular Surgery took a breath. In the end, after joint diagnosis and treatment by experts from multiple disciplines, the patient was successfully disarmed, and Mr. Luan was also discharged smoothly recently.

Four months ago, 73 year old Mr. Luan suddenly experienced persistent abdominal pain and difficulty in defecating. The local hospital diagnosed him with "umbilical hernia with small intestinal impaction and obstruction" and performed exploratory laparotomy and hernia repair surgery. However, two months after the surgery, the wound did not heal for a long time, and the stomach became increasingly swollen. As time goes by, even fist sized bulges grow around the edge of the knife, and the nearby skin repeatedly breaks and becomes infected. This has caused a huge burden on Mr. Luan's physical and mental health, and his daily life has been severely affected.

"At first glance, I saw his huge belly. Due to the nearly 10 centimeter hernia, nearly half of the small and large intestine had already protruded outside the abdominal cavity," said Dong Zhihui.

The CT situation is even worse: the patient has an aneurysm in the thoracic aorta with a diameter exceeding 5.5 centimeters, which is nearly twice the diameter of a normal blood vessel. If it ruptures, the consequences are unimaginable. At the same time, a thin layer of skin on the abdominal wall surrounds the protruding abdominal organs, with the thinnest area only 1.9 millimeters, and there are two 4x3 and 3x2 ulcers on the belly, which are at risk of breaking through at any time.

Dong Zhihui consulted Professor Fu Weiguo, Director of Vascular Surgery, and collaborated with Deputy Chief Physician Yang Ziang of General Surgery and Deputy Chief Physician Zhang Xiaoguang of Anesthesiology Department for multidisciplinary consultations. After thorough discussion, experts have decided to have vascular surgery perform endovascular treatment on the aneurysm first, remove the life-threatening time bomb, and then have general surgery repair the abdominal wall defect.

Older age, obesity, underlying diseases, poor postoperative recovery, and the need to undergo two consecutive surgeries... Doctors and patients face too many challenges to overlook.


Unexpectedly, the internal organs have come out! The multidisciplinary team of Zhongshan Hospital successfully dismantled the bomb, and the grandfather's abdomen was as huge as a pregnancy in October. Surgery | blood vessels | viscera

How to remove the "time bomb" in the chest while controlling the size of the trauma? After careful consideration, Dong Zhihui decided to insert a covered stent to isolate the aneurysm, reduce the impact of blood flow on the tumor, and achieve the goal of preventing tumor rupture. After developing a detailed surgical plan, the experts only successfully removed the bullet through a incision of less than 1 centimeter. The day after the surgery, Mr. Luan transferred to the general surgery department and waited for subsequent hernia repair surgery.

In the face of huge abdominal wall defects and repeated skin ulcers and infections, Dr. Yang Ziang of the General Surgery Department decided to have Mr. Luan carry out sufficient preoperative preparation, wear abdominal straps every day to compress the abdomen, adapt to the state of intestinal return into the abdominal cavity in advance, and blow balloons to exercise lung function and avoid postoperative pulmonary dysfunction.

Two weeks later, Dr. Yang Ziang led a team to perform a "tension-free repair surgery for giant abdominal incisional hernia" for Mr. Luan. During the surgery, he discovered that due to repeated skin infections in the past, an inflammatory mass with a diameter of about 6 centimeters had formed below Mr. Luan's navel. How to remove inflammatory masses and then perform abdominal wall repair has become a thorny problem. If no patch is used, it is almost impossible to successfully repair a huge abdominal wall defect; Once a patch is used, if a postoperative infection occurs, the patch becomes a foreign body that breeds bacteria and needs to be removed again, resulting in repair failure.

In response to this special situation, Dr. Yang Ziang used the Frame technique to divide the hernia sac peritoneum into upper and lower sections. The lower section closed a huge hernia ring with a diameter of about 11 centimeters. A patch was placed in front of the peritoneum, and the upper section of the peritoneum was used to cover and isolate the patch. Finally, the muscle layers of the abdominal wall that had moved apart on both sides were sutured and pulled together. After 3 hours of surgery, Mr. Luan's damaged abdominal wall was successfully repaired, and the second "bomb" was dismantled from then on.

After undergoing two surgeries, the "ball" in Mr. Luan's stomach finally disappeared, and the patient's recovery is currently good.

Why is "Cancer King" immunotherapy ineffective? Fudan Cancer Hospital Reveals New Mechanisms of Immunosuppressive Environment for pancreatic cancer CRIP1 | Tumor | pancreatic cancer
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Immunotherapy has been proven to achieve significant therapeutic effects in various solid tumors. However, for pancreatic cancer, known as the "king of cancer", immunotherapy has been ineffective. On August 4, Professor Yu Xianjun, Dean of the Cancer Hospital Affiliated to Fudan University, and Shi Si, Associate Professor of Pancreatic Surgery released a research achievement, which first found the key role of cysteine rich protein 1 in shaping the immunosuppressive microenvironment of pancreatic cancer, filled the gap in the research field of immunosuppressive microenvironment of pancreatic cancer, and provided a theoretical basis for precise immunotherapy of pancreatic cancer patients. Ductal adenocarcinoma of the pancreas is the main type of pancreatic cancer, accounting for about 90% of all pancreatic cancer. Due to its high malignancy and poor treatment effectiveness, pancreatic ductal adenocarcinoma has always been one of the most malignant tumors. In recent years, the level of surgical techniques and comprehensive treatment has been achieved

A 14-year-old girl suffers from a rare eye disease and receives support from a public welfare fund. Symptoms of "I haven't looked in the mirror for a long time" | Patient | Public welfare
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A 14-year-old girl has been experiencing symptoms such as protruding pupils, incomplete eye closure, corneal injury, restricted eye movement, and overall fatigue for several years. The physical discomfort and facial abnormalities caused by eye diseases have made her increasingly reticent, and her temperament is vastly different from before. At the Ophthalmology Department of the Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, the pupil has been diagnosed with a rare thyroid ophthalmopathy combined with myasthenia gravis, which requires prompt treatment. However, considering the young age of the pupil, conventional hormone and radiation therapy cannot be used. Therefore, Zhou Huifang, Deputy Director of Ophthalmology and thyroid ophthalmology expert, has developed a targeted drug combined with surgical treatment plan for it, and targeted drug treatment will be performed first. Three months ago, I was hospitalized for one week with mydriasis and received intravenous targeted drug treatment. Afterwards, I went home for observation and followed up on time

The municipal eye disease prevention and treatment center launched the dry eye diagnosis and treatment studio, and the incidence rate of dry eye in China is about 21% to 30% of the meibomian gland | dry eye | eye disease
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According to the Statistics of Chinese Dry Eye Expert Consensus, the incidence rate of dry eye in China is about 21%~30%, and it is estimated that there are at least 300 million patients nationwide. The Dry Eye Diagnosis and Treatment Studio of Shanghai Eye Disease Prevention and Treatment Center was officially launched today. In the future, the studio will continuously improve the dry eye diagnosis and treatment standards, and form standardized diagnosis and treatment concepts and service models. Suitable technologies will be promoted to the community, allowing residents to enjoy convenient dry eye diagnosis and treatment services at their doorstep. Executive Dean and Party Secretary Gao Wei stated that this is also one of the livelihood service measures recently launched by the hospital around high-quality development and meeting the needs of the people. It is reported that dry eye syndrome is a chronic ocular surface disease caused by multiple factors. The instability of the tear film or imbalance of the ocular surface microenvironment caused by abnormal quality, quantity, and dynamics of tears can be accompanied by ocular surface inflammatory reactions, tissue damage, and nerve abnormalities, resulting in various discomforts in the eyes

The Ninth Hospital has taken the lead in formulating the world's first consensus on core indicators for clinical evaluation of dental implants, which has been officially published in clinical practice
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Recently, autologous hematopoietic stem cell therapy was completed in Shanghai, and British girls born in the 1990s have suffered from multiple relapses of blood diseases, including stem cells, peripheral blood, and diseases
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Recently, Catherine, a British girl born in the 1990s, received autologous peripheral blood hematopoietic stem cell transfusion at the Cancer Center of Shanghai Jiahui International Hospital, and was successfully discharged from the warehouse. She is now on her way back to China after being discharged from the hospital. She is also the first patient at Shanghai Jiahui International Hospital to complete relevant treatments. In 2019, Catherine was diagnosed with Hodgkin's lymphoma in the UK, and after treatment, the disease completely improved. During her work and life in China in 2021, she went to seek medical attention due to multiple enlarged lymph nodes. Pathological biopsy confirmed a recurrence of Hodgkin's lymphoma, and through combined targeted drug treatment, her condition was temporarily under control. Last year in the second half of the year, when the disease recurred, the girl began to use immunotherapy combined with targeted drugs for treatment. Expert evaluation suggests that for young patients with hematological tumors, the risk of recurrence is high and treatment difficulty is increasing in the future. Autologous hematopoietic stem cell therapy is recommended