Renji Hospital and Cancer Hospital jointly store 26 "sparks of life". A 29 year old unmarried woman suffers from lymphoma. Team | Patient | Renji Hospital

Release time:Apr 15, 2024 02:30 AM

At the age of 29, Mengmeng has not yet married and given birth, but unfortunately suffers from malignant lymphoma. After receiving tumor treatment, she is likely to "lose" her fertility. Recently, the Reproductive Medicine Center of Renji Hospital affiliated with Shanghai Jiao Tong University School of Medicine successfully completed egg freezing for Meng Meng who was referred to Fudan University Affiliated Cancer Hospital, storing 26 "life sparks" - precious eggs.

 

Unmarried women diagnosed with malignant tumors, chemotherapy damage ovarian function

Unmarried women diagnosed with malignant tumors, chemotherapy damage ovarian function

In June of this year, Mengmeng suddenly discovered a lump in her neck. After examination at the local hospital, she highly suspected malignant disease. So, Mengmeng came to Shanghai to seek medical treatment at a tumor hospital. After a biopsy, she was diagnosed with diffuse large B-cell lymphoma.


Renji Hospital and Cancer Hospital jointly store 26 "sparks of life". A 29 year old unmarried woman suffers from lymphoma. Team | Patient | Renji Hospital

Liu Xiaojian, the chief physician of the Oncology Department at the Cancer Hospital, told Mengmeng that the current treatment effect for this type of lymphoma is still relatively optimistic, but the chemotherapy process can cause irreversible damage to ovarian function. It is reported that the process of radiotherapy and chemotherapy in cancer patients can lead to follicular apoptosis, which not only leads to the loss of fertility in some individuals, but also causes premature menopause and aging.

 

Meng Meng, who is only 29 years old, has not yet married or had children. If she loses her fertility after tumor treatment, it will undoubtedly have a huge impact on her future life. Therefore, Liu Xiaojian suggests that Mengmeng seek help with fertility preservation at the Reproductive Medicine Center of Renji Hospital as soon as possible.

Mengmeng was quickly referred to the fertility preservation team at the Reproductive Medicine Center of Renji Hospital. Attending physician Zhang Chuyue learned that Mengmeng's specific chemotherapy plan will use drugs such as alkylating agents that cause serious damage to ovarian function. After further evaluating the ovarian reserve function, the director of the Department of Reproductive Medicine, Sun Yi, developed a fertility preservation plan and quickly initiated ovulation induction therapy for the sprouts without affecting the tumor treatment process.

Renji Cancer Hospital and Hospital jointly worked to freeze 26 "life sparks"


Renji Hospital and Cancer Hospital jointly store 26 "sparks of life". A 29 year old unmarried woman suffers from lymphoma. Team | Patient | Renji Hospital

Mengmeng was quickly referred to the fertility preservation team at the Reproductive Medicine Center of Renji Hospital. Attending physician Zhang Chuyue learned that Mengmeng's specific chemotherapy plan will use drugs such as alkylating agents that cause serious damage to ovarian function. After further evaluating the ovarian reserve function, the director of the Department of Reproductive Medicine, Sun Yi, developed a fertility preservation plan and quickly initiated ovulation induction therapy for the sprouts without affecting the tumor treatment process.

 

For cancer patients, perioperative safety is also of utmost importance. Before the egg retrieval surgery, Niu Yichao, the deputy chief physician of the fertility preservation team, and an anesthesiologist discussed and formulated a detailed risk prevention and control plan for bleeding, infection, and other factors.

The final egg retrieval surgery went smoothly, and after the surgery, combined with in vitro maturation technology of oocytes, 26 eggs were finally frozen for Mengmeng. These eggs can help her give birth to her own baby after her lymphoma treatment stabilizes and there are no contraindications for pregnancy.

Sun Yi revealed that it is gratifying that both oncologists and many young cancer patients are gradually moving out of the misconception of "saving lives before giving birth". Establishing an effective referral mechanism between oncologists and reproductive specialists can provide effective fertility assessment and preservation work for young patients who require fertility preservation in the first time.


Renji Hospital and Cancer Hospital jointly store 26 "sparks of life". A 29 year old unmarried woman suffers from lymphoma. Team | Patient | Renji Hospital

Fertility preservation has a "golden time window", and efforts should be made to "seize" resources

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