Do you know how to deal with negative emotions in daily life? 300 million people around the world are suffering from depression, and famous singers have passed away due to depression | Symptoms | Global

Release time:Apr 14, 2024 02:07 AM

Famous Chinese singer Li Wen passed away due to depression, causing countless fans to mourn. In fact, depression is one of the most common mental disorders. According to statistics from the World Health Organization, there are 300 million people of all ages worldwide who suffer from depression. According to data from our country, the lifetime prevalence of depression among individuals is 6.8%. Many people are still hesitant and panicked when they hear about depression, unwilling to accept it. So what is depression? Dr. Shao Chunhong, Deputy Director of the Department of Psychiatry at Huashan Hospital affiliated with Fudan University, gave an explanation to readers.

Depression is a mood disorder characterized by significant and persistent mood swings. The patient's symptoms can manifest as mild depression, severe grief, and even hallucinations, delusions, suicidal thoughts or behaviors, affecting work, life, and study.

Why do people suffer from depression? Expert explanation: The etiology of depression is very complex, and there is currently no exact pathogenesis. However, existing scientific research results indicate that it is mainly caused by a combination of genetic and environmental factors. From a genetic perspective, insufficient production of neurotransmitters beneficial to emotions by individuals themselves, or increased sensitivity to stress responses such as stimuli and trauma, can lead to disease. From the perspective of environmental factors, including childhood or adolescence trauma, or adverse environments or events encountered throughout life, can cause illness.

Depression is not just an emotional issue, it can also lead to emotional, physical, and cognitive symptoms.

Emotional symptoms mainly refer to the symptoms that patients are least willing to accept or admit, like the hidden parts under an iceberg, which require careful consultation by doctors to discover. Specifically, it manifests as a decrease in interest in things or activities that were previously enjoyed, or a loss of interest. Even if you persist in doing it, there is no sense of pleasure. Clinically, it is common to see that patients will give up some activities they originally enjoyed, such as sports activities, extracurricular activities, social interactions, etc., and they will not even be interested in daily work, life enjoyment, etc. Some are accompanied by obvious nervousness, worry, etc.

Physical symptoms are what patients are most willing to express, like the exposed part of an iceberg, which is more likely to attract attention. Often manifested as patients seeking medical treatment in various departments of a comprehensive hospital, but no major problems were found in various examinations. Physical symptoms include sleep disorders; Feeling weak and fatigued throughout the body; Panic, chest tightness, stomach discomfort, diarrhea and constipation; Changes in appetite and weight, etc.

Cognitive symptoms are of greater concern in elderly patients with depression. Once cognitive symptoms appear, it is easy to worry about developing senile dementia, exacerbating feelings of pricelessness and self blame. Cognitive symptoms mainly manifest as lack of concentration, decreased memory, and delayed thinking. Patients may feel that their brain is becoming dull, the thinking process is difficult, and some simple problems may take a long time to complete.

How to determine if you have depression?


Do you know how to deal with negative emotions in daily life? 300 million people around the world are suffering from depression, and famous singers have passed away due to depression | Symptoms | Global

Taking the fifth edition of the Diagnostic and Statistical Manual in the United States as an example, the diagnostic criteria for depression are as follows:

Within two consecutive weeks, there were significant functional changes that were different from before, manifested as more than five of the above, of which at least one was mood depression or loss of interest and pleasure.

These symptoms cause obvious pain or functional impairment in social, occupational, or other important aspects;

These symptoms are not caused by any substance or other physical condition.

If you want to know if you may experience depression, you can also use a simple 9-item patient health self-assessment questionnaire for screening. However, this scale only indicates that there may be corresponding levels of depressive symptoms, and diagnosis must be made through formal and detailed examination by a specialist, and appropriate treatment methods should be selected according to the patient's condition.

Scoring rules and treatment recommendations for the PHQ-9 scale:

0-4 points without depression

5-9 points for mild depression


Do you know how to deal with negative emotions in daily life? 300 million people around the world are suffering from depression, and famous singers have passed away due to depression | Symptoms | Global

10-14 points moderate depression

15-19 points for moderate to severe depression

20-27 points for severe depression

Finally, Shao Chunhong reminds citizens not to suspect depression just because they feel sad or unhappy. Depression is a negative emotion, characterized by low mood and decreased interest in activities. Like happiness and anger, it is a normal psychological response. Normal people will experience similar emotions when encountering stress in unfavorable situations, with a short duration and little need for medical treatment.

However, citizens should also learn to monitor their own emotional changes. For negative emotions, it is necessary to analyze the causes, face them squarely, accept them, observe their duration and severity, actively adopt methods such as changing attention, adjusting thoughts, exercising moderately, eating a healthy diet, regular sleep patterns, as well as pouring out and seeking professional help, so as to let negative psychology go smoothly and prevent the occurrence of depression. Even if diagnosed with depression, as long as appropriate medication, psychological or physical treatment methods are selected with the help of regular specialist doctors, and standardized treatment throughout the entire disease process is adhered to, depression is not invincible.

Why is "Cancer King" immunotherapy ineffective? Fudan Cancer Hospital Reveals New Mechanisms of Immunosuppressive Environment for pancreatic cancer CRIP1 | Tumor | pancreatic cancer
Why is "Cancer King" immunotherapy ineffective? Fudan Cancer Hospital Reveals New Mechanisms of Immunosuppressive Environment for pancreatic cancer CRIP1 | Tumor | pancreatic cancer

Immunotherapy has been proven to achieve significant therapeutic effects in various solid tumors. However, for pancreatic cancer, known as the "king of cancer", immunotherapy has been ineffective. On August 4, Professor Yu Xianjun, Dean of the Cancer Hospital Affiliated to Fudan University, and Shi Si, Associate Professor of Pancreatic Surgery released a research achievement, which first found the key role of cysteine rich protein 1 in shaping the immunosuppressive microenvironment of pancreatic cancer, filled the gap in the research field of immunosuppressive microenvironment of pancreatic cancer, and provided a theoretical basis for precise immunotherapy of pancreatic cancer patients. Ductal adenocarcinoma of the pancreas is the main type of pancreatic cancer, accounting for about 90% of all pancreatic cancer. Due to its high malignancy and poor treatment effectiveness, pancreatic ductal adenocarcinoma has always been one of the most malignant tumors. In recent years, the level of surgical techniques and comprehensive treatment has been achieved

A 14-year-old girl suffers from a rare eye disease and receives support from a public welfare fund. Symptoms of "I haven't looked in the mirror for a long time" | Patient | Public welfare
A 14-year-old girl suffers from a rare eye disease and receives support from a public welfare fund. Symptoms of "I haven't looked in the mirror for a long time" | Patient | Public welfare

A 14-year-old girl has been experiencing symptoms such as protruding pupils, incomplete eye closure, corneal injury, restricted eye movement, and overall fatigue for several years. The physical discomfort and facial abnormalities caused by eye diseases have made her increasingly reticent, and her temperament is vastly different from before. At the Ophthalmology Department of the Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, the pupil has been diagnosed with a rare thyroid ophthalmopathy combined with myasthenia gravis, which requires prompt treatment. However, considering the young age of the pupil, conventional hormone and radiation therapy cannot be used. Therefore, Zhou Huifang, Deputy Director of Ophthalmology and thyroid ophthalmology expert, has developed a targeted drug combined with surgical treatment plan for it, and targeted drug treatment will be performed first. Three months ago, I was hospitalized for one week with mydriasis and received intravenous targeted drug treatment. Afterwards, I went home for observation and followed up on time

The municipal eye disease prevention and treatment center launched the dry eye diagnosis and treatment studio, and the incidence rate of dry eye in China is about 21% to 30% of the meibomian gland | dry eye | eye disease
The municipal eye disease prevention and treatment center launched the dry eye diagnosis and treatment studio, and the incidence rate of dry eye in China is about 21% to 30% of the meibomian gland | dry eye | eye disease

According to the Statistics of Chinese Dry Eye Expert Consensus, the incidence rate of dry eye in China is about 21%~30%, and it is estimated that there are at least 300 million patients nationwide. The Dry Eye Diagnosis and Treatment Studio of Shanghai Eye Disease Prevention and Treatment Center was officially launched today. In the future, the studio will continuously improve the dry eye diagnosis and treatment standards, and form standardized diagnosis and treatment concepts and service models. Suitable technologies will be promoted to the community, allowing residents to enjoy convenient dry eye diagnosis and treatment services at their doorstep. Executive Dean and Party Secretary Gao Wei stated that this is also one of the livelihood service measures recently launched by the hospital around high-quality development and meeting the needs of the people. It is reported that dry eye syndrome is a chronic ocular surface disease caused by multiple factors. The instability of the tear film or imbalance of the ocular surface microenvironment caused by abnormal quality, quantity, and dynamics of tears can be accompanied by ocular surface inflammatory reactions, tissue damage, and nerve abnormalities, resulting in various discomforts in the eyes

The Ninth Hospital has taken the lead in formulating the world's first consensus on core indicators for clinical evaluation of dental implants, which has been officially published in clinical practice
The Ninth Hospital has taken the lead in formulating the world's first consensus on core indicators for clinical evaluation of dental implants, which has been officially published in clinical practice

The International Dental Implant Consensus Report, jointly written by the Ninth People's Hospital affiliated with Shanghai Jiao Tong University School of Medicine and renowned universities in the field of dentistry such as Harvard University, University of Zurich, University of Gothenburg, Columbia University, and University of Frankfurt, has recently been jointly published in top journals in the field of dentistry, including Clinical Periodontology and Clinical Dental Implant Research. This consensus has for the first time established an internationally unified core set of indicators for evaluating the clinical effectiveness of dental implants, covering the five key areas of the field of dental implants. It is of milestone significance for carrying out standardized clinical diagnosis, treatment, and research on dental implants. The core evaluation indicators determined by this consensus will become an important benchmark for scholars in the field of dental implants worldwide to conduct high-quality research. The consensus is composed of 8 top international experts in the field of oral implantation

Recently, autologous hematopoietic stem cell therapy was completed in Shanghai, and British girls born in the 1990s have suffered from multiple relapses of blood diseases, including stem cells, peripheral blood, and diseases
Recently, autologous hematopoietic stem cell therapy was completed in Shanghai, and British girls born in the 1990s have suffered from multiple relapses of blood diseases, including stem cells, peripheral blood, and diseases

Recently, Catherine, a British girl born in the 1990s, received autologous peripheral blood hematopoietic stem cell transfusion at the Cancer Center of Shanghai Jiahui International Hospital, and was successfully discharged from the warehouse. She is now on her way back to China after being discharged from the hospital. She is also the first patient at Shanghai Jiahui International Hospital to complete relevant treatments. In 2019, Catherine was diagnosed with Hodgkin's lymphoma in the UK, and after treatment, the disease completely improved. During her work and life in China in 2021, she went to seek medical attention due to multiple enlarged lymph nodes. Pathological biopsy confirmed a recurrence of Hodgkin's lymphoma, and through combined targeted drug treatment, her condition was temporarily under control. Last year in the second half of the year, when the disease recurred, the girl began to use immunotherapy combined with targeted drugs for treatment. Expert evaluation suggests that for young patients with hematological tumors, the risk of recurrence is high and treatment difficulty is increasing in the future. Autologous hematopoietic stem cell therapy is recommended